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People who smoked cannabis had higher blood flow through their brains than non-users. Yet there was also greater resistance to the blood flow, suggesting that cannabis changes the blood vessels in the brain in a way which hinders oxygen in reaching the tissue effectively. In an attempt to compensate, extra blood is sent to that part of the brain, increasing resistance but probably failing to get enough oxygen through the vessels, Cadet suggests. Cadet and his colleagues used an extremely sensitive non-invasive technique called transcranial Doppler sonography to “see” the blood flow through individual arteries from the head’s surface. After a month without cannabis – during which the volunteers agreed to remain in a clinic, with no access to marijuana – Cadet repeated the sonography.

The resistance to blood flow of light and moderate users – who usually smoked an average of 11 and 44 joints per week, respectively – was starting to return to normal. But there was no improvement observed in the heavy users, who smoked an average of 131 joints per week. “We were surprised because we’d expected that as marijuana cleared the system things would improve,” says Cadet. He now wants to see if there is a link between the changes in the brain’s blood flow and the extent of neuropsychological problems. To eliminate the effect of tobacco in the joints, Cadet compared his results to those obtained from smokers, who showed normal blood flow. But, says William Notcutt of James Paget Hospital in Norfolk, UK, the longer-term effect on the brain may not have been caused by the same substance that produces the high. “Somebody smoking 50 joints per day is getting a huge number of carcinogens from the marijuana plant,” he notes. “We know the cardiovascular effect [of cannabis] is very complex and multi-factorial so it’s not as simple as with other drugs.

The group that needs to be studied now is people that use high quality medicinal extracts.” He adds that the results may also be different for people that only smoke marijuana occasionally, and so are exposed to lower doses of the toxic substances. Journal reference: Neurology (vol 64, p 488) Synthetic Pot Linked To Bleeding From Eyes And Ears. The already known risks of using synthetic marijuana now come with an added warning--bleeding from your eyes and ears--based on recent news reports from a number of communities in Chicago. Synthetic Pot (Courtesy of Ed Zurga/Bloomberg) In a statement released by the Illinois Department of Public Health (IDPH), 6 people recently suffered severe bleeding from their eyes and ears after using synthetic cannabinoids March 7th. Today, that number increased to 32, according to an updated IDPH report. This should be sufficient warning to discourage you from using this dangerous and unpredictable concoction, especially if you had any prior doubts or concerns in your mind. “Despite the perception that synthetic cannabinoids are safe and a legal alternative to marijuana, many are illegal and can cause severe illness,” said IDPH Director Nirav D. “ The recent cases of severe bleeding are evidence of the harm synthetic cannabinoids can cause .” Known by popular names such as K2 or Spice, synthetic cannabinoids are highly unpredictable in the effects they may produce . But that’s to be expected when you spray dried plant material with any number of toxic chemicals including insecticides, as well as unknown and untested cannabinoids. Synthetic cannabinoids act on the same receptors in the brain as the main active ingredient in marijuana, THC . However, synthetic cannabinoids do not contain the active ingredient (THC) in cannabis; instead, they contain a myriad of dangerous and often unidentified chemicals. It’s akin to playing Russian Roulette, since it's unknown what exactly is contained in the product. It's believed that synthetic cannabinoids have a greater affinity for the CB1 receptor compared to THC, and that this greater affinity is responsible for its more unpredictable and toxic effects. Synthetic cannabinoids have been linked to intractable vomiting, aggressive behavior and agitation, hallucinations, seizures, strokes, kidney failure, coma and death, according to the CDC. It’s unclear what is contained in the new batch of synthetic pot that could cause bleeding, but Dr. Jerrold Leikin, Director of Toxicology at Northshore University Health System, believes it's most likely an anticoagulant or blood thinner, he told NBC Chicago. While anticoagulants or blood thinners have different mechanisms of action at various points in the coagulation cascade, the net effect is to cause bleeding. Some of the bleeding could be life threatening, involving the brain, GI tract, upper airway or lungs. In recent reports related to use of synthetic cannabinoids coming out of Chicago, bleeding involved only the eyes or ears, but updated reporting by USA Today now includes nose bleeds, bloody urine and bleeding in the brain. The message is loud and clear: stay away from this dangerous substance, and educate all family members that use of this could be deadly. T he number one problem with pipe smoking is how to pack a pipe! Uncle Bob is constantly reinforcing the proper procedures to all his customers who have all found this method efficient and easy to use. I f you are experiencing "tongue bite" or "dottle" at the bottom of your pipe, chances are you are packing your pipe too tightly. Even if you never smoke all the tobacco in the pipe, it probably isn't the pipe but the packing! U ncle Bob says that these procedures are proven and effective.

Try them in your worst smoking pipe with your hottest blend and see if it doesn't make a big difference!

Although differing qualities of pipes and tobaccos will make a difference, you can take any pipe and smoke any tobacco in that pipe if you pack it right.


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