They have to endure a long process throughout the body first. But because smoking marijuana produces an oxidization process, cannabinoid absorption is relatively high. This is because molecules do not pass through the acidic stomach environment, but rather go into the bloodstream through the lungs. Long story short: The higher the bioavailability, the lower dosage you need to produce the desired result.
Cannabinoids from combusted cannabis are absorbed rather quickly, so holding in your hit too long will result in unwanted absorption of smoke and tars. In fact, approximately 88% of combusted smoke gasses (think joints and bongs) contain non-cannabinoid elements. Smoking produces a rapid effect that lasts for a short time due to its high bioavailability, so the general recommendation is that holding it for a few seconds should do the trick. Holding a huge hit just produces more smoke than your lungs can handle and it can’t go anywhere but out. Cannabis that is vaporized or dabbed, on the other hand, is cleaner and contains less tars or other non-cannabis elements (It’s also perceived as much safer than smoking). Some say that nearly 95% of cannabinoids are inhaled through vaporization.
But when looking at bioavailability, it’s about the same as combusted cannabis. Because you’re only consuming vapor though, holding in your hit slightly longer when vaporizing or dabbing won’t absorb any extra tars or smoke. Although each vaporizer and consumer can alter the dosage, you should still generally hold your hit for a few seconds to get the best results. If you’re inhaling from a joint or blunt, your lungs expand to pick up oxygen and the cannabinoids to then pass them to your blood vessels. This transportation process runs throughout your entire body and is how you get high. Instead of holding your hit for as long as possible, consider inhaling it more deeply into your lungs. Deeper breathing fills the lungs with up to five liters of air (shallow breathing only gets you 0.5 liters) which gives cannabis more room to enter the bloodstream. Although there is much speculation on how long to hold a hit in, there does seem to be some consensus on a magic number. Many sources say that three seconds is the prime hold time. It’s just enough to give your lungs the right amount of time to move as many cannabinoids as possible to your bloodstream while preventing your brain from being too deprived of oxygen. So, to get the most out of your next cannabis purchase, think about how you’re consuming your marijuana and take each hit appropriately. Consider inhaling a bit of clean air after a rip and take time between hits to let your body absorb the cannabinoids at their own speed. We always encourage experimentation, so get out a timer and run some tests to discover the best time and intensity for you. If you have finished growing, drying and curing, it is time to consume it. There are many ways to consume marijuana, one of them being vaporizing. First of all, what is a QWISO (Quick-Wash ISOpropyl) extract? Cannabis buds consist of two main parts – plant material and, what I like to call, “effective material”, which gives all the desired effects from consuming it. In other words, plant material is more or less useless. An extract (also called concentrate, shatter, wax, oil, budder) basically contains only the desired “effective material”, and is intended for many uses, but mainly for vaporizing. Making extracts isn’t as difficult as you may think, just requires some patience. There are several different methods for making high-quality extracts (other popular being BHO, but it is way more dangerous and complex due to usage of highly flammable butane, so I will stick to QWISO method). ITEMS YOU WILL NEED: Buds, at very least 5 grams of it, though the more the better (10-20 grams is optimal). Isopropyl alcohol, the purer, the better, 99% recommended. You can get it from hardware or electronics stores. You will need around 100 - 200 ml of it per 10 grams of buds. Or 2 sieves – one smaller and one as large as possible, if you’re making over 10 grams. A plate or other flat ceramic or glass surface (note: it must be quite deep, since you will be pouring quite a lot of liquid there). 1 small jar (up to 0.5 litre) and 1 larger jar (0.5-1 litre should be enough).
(optional, but highly recommended) a simple air-blowing fan. PREPARATIONS TO BE MADE AT LEAST 3 HOURS BEFORE THE EXTRACTION: First of all, make sure all containers (both jars and a plate) are really clean and totally dry (you want them totally clean, since the unwanted material might get into the extract, causing you problems later trying to remove it, and you want them dry, since water evaporation takes way longer than alcohol). Firstly grind up all your buds into the small jar (ground buds have larger surface area, so it is easier to extract all the goods from them that way). Then put that jar and your alcohol into a freezer for a few hours or just overnight to make sure they’re as cold as possible (don’t worry, isopropyl freezes only at -89 C). Freezing is necessary, since trichromes fall off the leaves of the bud way more easily at low temperatures, making the extraction significantly more successful. Extracting without freezing results in smaller amounts of the final product. You may also want to prepare your larger jar to save time later: take 1 coffee filter and put it onto your jar making sort of a bag (note: I used some thread to make sure the filter doesn’t fall into the jar), or, if you are making lots of extraction, cover entire surface of your larger sieve with filters and place smaller sieve on top of it.
ONCE ALCOHOL AND MATERIAL ARE BOTH AS COLD AS POSSIBLE: Pour alcohol into the small jar till all the ground buds are submerged in it. Close the lid very tightly and shake it as hell for exactly 30 seconds (more might result in more chlorophyll extracted, making the final product taste not as good, less might result in smaller amounts of the extract). Then pour everything through a sieve and through a filter into a jar (you may press the ground material in the first sieve to make it sieve though a bit faster). Yes, this part will be very slow, you will need patience, filtering might take 20-60 minutes.